Efficacy of azithromycin combined with budesonide for chronic sinusitis polyps
Zhao Hongqin
Han Xue
Deng Lina
Abstract：Objective To analyze the curative effect of budesonide nasal spray therapy in patients with chronic sinusitis.Methods The patients with chronic sinusitis and nasal polyps were selected and ended in 2020.3 from 2022.3.A total of 120 patients were grouped and treated by blind lottery.In the reference group(60 cases),the study group(60 cases)provided serum inflammation level and eosinophils level before and after treatment.Results The study group was more effective(96.67％)than the reference group(86.67％)(P＜0.05).The serum levels of inflammatory factors were similar before treatment(P＞0.05).After treatment,the IL-8(16.34±4.72)ng/L and CRP levels(3.15±0.49)mg/L were lower than those in the reference group(P＜0.05).Eosinophil levels were similar before treatment(P＞0.05),and the study group(9.85±3.31)0.25mm2/and 3 months(5.17±1.69)0.25mm2/were lower than the reference group(P＜0.05).Conclusion The combination of budesonide nasal spray treatment and azithromycin treatment in patients with chronic sinusitis nasal polyps can reduce eosinophils and has high clinical application value.
Keywords：Budesonide nasal spray treatmentChronic sinusitisNasal polypAzithromycin
Publication Date：2023-11-27
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 4-6 )