Study on the prevention of lower respiratory tract infection after the continuous operation of the patients with laryngeal complete resection of the inferior vena cava

Li Yi; Liu Caimin; Zhang Lingmin; Ma Wenlai

Abstract：ObjectiveTo explore the clinical effect of continuous negative pressure suction for the prevention of lower respiratory tract infection in patients with laryngeal squa-mous cell carcinoma.Methods40 patients with laryngeal carcinoma were randomly divided into two groups:20 cases in the control group and 20 cases in the observation group. For the observation group,continuous application of negative pressure suction device,the control group does not apply. Fungal and bacterial cultures were performed on the first day of treatment and at every three days. The above operation is strictly carried out under sterile conditions. The incidence of lower respiratory tract infection in two groups was observed,and the colony culture of airway was observed.ResultsThe incidence of respiratory infection in patients with the control group(40%) than in the observation group(15%)was significantly high-er,the difference was statistically significant(P<0.05);gram positive cocci were found,the observation group(5%) was significantly lower than the control group(25%), the difference was statistically significant(P<0.05);gram negative bacteria colony detection rate,the observation group(15%)was significantly lower than the control group (35%),the difference was statistically significant(P<0.05);non fermenting bacteria colony detection rate, the observation group(10%)was significantly lower than the control group(25%),the difference was statistically sig-nificant(P<0.05).ConclusionContinuous aspiration of inferior vena cava in patients after total laryngectomy can significantly reduce the various bacteria and fungi retention rate of the upper respiratory tract,while avoiding the incidence of lower respiratory tract infection rate,it is worthy of clinical application.