The influence on serum C reactive protein in patients with allergic rhinitis and bronchial asthma treated by Montelukast sodium and Fluticasone nasal spray
Guo Liangbin
Jiang Yongqin
Abstract：Objective To investigate the influence on serum C reactive protein in patients with allergic rhinitis and bronchial asthma treated by montelukast sodium and flutica-sone nasal spray. Methods 100 cases of allergic rhinitis with bronchial asthma were enrolled in this study from Febru-ary 2010 to February 2015. According to the random number table,patients were divided into observation group and control group. The control group was treated with montelukast sodi-um,while the observation group was treated with montelukast sodium and fluticasone nasal spray. Serum C reactive protein level,clinical symptoms,signs disappeared time and treat-ment efficacy were observed. Results C reactive protein level in the observation group(5.03±1.02)mg/L was less than that of the control group(18.92±3.02)mg/L,and the difference was statistically significant(P<0.05). Asthma disappearance time, rales disappearance time,cough disappeared time,antipyretic time,hospitalization time in observation group(2.52±0.71, 4.56±0.63,6.93±1.31,4.52±1.01,7.53±1.24),were low-er than control group(3.92±1.03,5.80±0.82,10.39±2.04, 5.31±1.30,12.49±2.05),and the differences were statistically significant(P<0.05);The total effective rate was 98%in obser-vation group,while in the control group was 80%,and the differ-ence was statistically significant(P<0.05). Conclusion The curative effect of montelukast sodium and fluticasone nasal spray in treating allergic rhinitis and bronchial asthma is remarkable,and can reduce the levels of C-reactive protein.
Keywords：Montelukast sodiumfluticasone nasal sprayRhinitisAllergicPerennialbronchial asthmaC reactive protein
Publication Date：2016-05-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 136-139 )