Correlation analysis of EB virus infection and tonsils and adenoid hypertrophy in children

Zou Lili

Abstract：ObjectiveTo study the correlation of children epstein-barr virus(EBV)infection and tonsils and adenoid hyper-trophy in children.MethodsSeventy children with tonsil and adenoid hypertrophy from the June 2013 to June 2014 in our hospital were included in this research. According to the children age,sex, weight,etc,they were divided into different groups. And EBV infection was evaluated and compared.ResultsIn 70 cases of children with adenoid hypertrophy were tonsils,a total of 47 cases with EBV infection. Among the EBV-DNA positive cases,the male children accounted for 66.67%(30/45),while female patients accounted for 68.00%(17/25). There was no significant difference (P<0.05). Preschool EBV infection was 66.67%(22/33)and 67.57%(25/37)in school-age children,there was no significant difference(P> 0.05). The EBV infection rate in children with a duration of disease less than 30 months was 62.50%(30/48), 78.57%(11/14) with duration of 30 to 60 months,75%(6/8)with duration>60 months . EBV infection rates among the three groups had no significant difference(P>0.05). EBV infection rate in children of body weight of 0~20 kg was 70.59%(12/17),69.05%(29.42) of 20~40 kg,54.55%(6/11)of 40~60 kg. Children with different weight had no significant difference in EBV infection(P>0.05). EBV infection in children with snoring accounted for 68.63%(35/51), 63.16%(12/51)in children without snoring. There was no significant difference(P>0.05)between the two groups.ConclusionEBV infection among children has relevance to tonsil and adenoid hypertrophy. EBV in tonsil and adenoid tissues showed no significant correlation with the patient's age,sex,weight,duration of disease.