Combined depistage of hearing screening and deafness gene for childhood late onset hearing impairment
Abstract：Childhood late-onset hearing loss of children has a high incidence in China,which affects speech development and leads to heavy burden to the family and society. The newborn hearing screening system couldn't effectively recognize these children even with the registration of potential risk factors. P.V37I homozygous mutations of GJB2 gene is proved to be risk factor of late-onset hearing impairment. A screening technique by using high resolution melting has been created to detect the p.V37I mutation,which could predict the late-onset hearing impairment and make early intervention by combining the newborn hearing screening.
Keywords：Auditory Perceptual DisordersNeonatal ScreeningDeafnessGene
Publication Date：2015-07-02
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 189-191 )