Clinical evaluation of Xintong No.2 combined with atorvastatin in the treatment of AMI after PCI
ZHANG Jing
GAO Yunhe
GAO Xianxi
Abstract：Objective To explore the effect of Xintong No.2 combined with atorvastatin on cardiac function,platelet function,and restenosis rates of patients with acute myocardial infarction(AMI)following percutaneous coronary intervention(PCI).Methods A total of 100 patients undergoing PCI admitted to Tangshan Hospital of Traditional Chinese Medicine from April 2020 to January 2022 were enrolled in the study and divided into the control group and the study group using a random number table method,with 50 cases in each group.The control group was given conventional intervention plus atorvastatin,and the study group was treated with conventional intervention plus atorvastatin plus Xintong No.2.The clinical data of the patients was collected,and the clinical efficacy,cardiac function,platelet function and restenosis rates were compared between the two groups.Results The total effective rate of the study group was 90.00％(45/50),higher than 74.00％(37/50)of the control group(x2=4.336,P=0.037).After treatment,the left ventricular ejection fraction and 6-minute walk test distance of the study group were(61.24±7.99)％and(423.77±52.57)m,higher than(55.33±7.02)％and(391.52±49.11)m of the control group(t=3.929,3.171,both P＜0.05),and the above indicators were higher than those before treatment.After treatment,the left ventricular end systolic diameter(LVESD)((21.27±3.05),(29.33±4.24)mm),left ventricular septal thickness(LVST)((8.66±1.55),(9.80±2.02)mm),left ventricular end diastolic diameter(LVEDD)((33.15±5.23),(45.67±6.68)mm),platelet aggregation rate(PAG)((22.66±5.02)％,(28.94±5.58)％),platelet membrane glycoprotein(GP)Ⅱb/Ⅲa((16.13±3.47),(21.85±4.84))and platelet adhesion rate(PAR)((26.67±6.22)％,(30.84±6.88)％)of the study group and the control group were lower than those before treatment,and the above indexes of the study group were lower than those of the control group(t=1 0.912,3.166,10.435,5.916,6.792,3.179,all P＜0.05).The incidence of postoperative restenosis in the control group and the study group was 16.00％(8/50)and 4.00％(2/50),respec-tively,and the difference was statistically significant(x2=4.000,P=0.046).Conclusion Xintong No.2 combined with atorvastatin has a definite effect in the treatment of AMI patients after PCI.It can improve the cardiac function and platelet function,and re-duce the incidence of postoperative restenosis.
Keywords：Xintong No.2atorvastatinpercutaneous coronary interventionplatelet functionpostoperative restenosis
Publication Date：2026-01-25
Online Publishing Date：2026-03-03(First online date of this platform, not the publication date of the document)
Pages：4( 131-134 )