Rationality evaluation of prophylactic antibiotic use in orthopedic surgical patients based on the attribute hierarchy model
Lu Tengfei
Fan Youfei
Zhang Qing
Abstract:Objective To investigate the rationality of prophylactic antibiotic use in patients undergoing orthopedic surgery based on the attribute hierarchy model(AHM).Methods The AHM was constructed to conduct a retrospective analysis of the in-patient medical records of 160 patients who underwent surgery in Department of Orthopedics,the People's Hospital of Bozhou from February 2019 to October 2024.Results The types of unreasonable prophylactic use of antibacterial agents in patients undergoing orthopedic surgery mainly included drug dose(41.25%(66/160)),medication course(36.88%(59/160))and drug allergy test before medication(34.38%(55/160)).Among them,the proportion of treatment courses lasting more than 48 hours was 36.88%(59/160).For cefuroxime dosing,the proportion of adult single doses exceeding 1.5 g and pediatric single doses exceeding 50 mg·kg-1 was 31.25%(50/160).Additionally,the proportion of cefuroxime skin tests conducted before medication was 28.75%(46/160).Regarding the medical record score(MRS),64 cases(40.00%)had an MRS of≥90 points,43 cases(26.88%)had an MRS between 85 and 89 points,30 cases(18.75%)had an MRS between 80 and 84 points,and 23 cases(14.38%)had an MRS of<80 points.Conclusion The rationality of prophylactic use of antibacterial drugs for patients undergoing orthopedic surgery is acceptable,but there is still considerable room for improvement.Further management needs to be strengthened in terms of drug dosage,course of medication and drug allergy test before medication.
Keywords:Attribute hierarchy modelDepartment of orthopedicsAntibacterial drugProphylactic useRationality evaluation
Publication Date:2025-08-25
Online Publishing Date:2025-09-01(First online date of this platform, not the publication date of the document)
Pages:4( 919-922 )
Chinese Journal of Drug Application and Monitoring

Chinese Journal of Drug Application and Monitoring

ISTIC
ISSN:1672-8157
Year, Vol.(Issue):2025,22(5)