Evaluation of lactulose and polyethylene glycol electrolyte solution for bowel preparation in pediatric colonoscopy
Cai Li-jun
Zhu Mao-long
Shu Meng
Yuan Wen-ying
Abstract：Objective To evaluate the efficacy of combining lactulose oral solution with polyethylene glycol electrolyte powder as a bowel preparation regimen prior to fiber colonoscopy in pediatric patients presenting with abdominal pain.Methods One hun-dred and two children who underwent fiberoptic colonoscopy for abdominal pain in Hubei Maternal and Child Health Hospital from January 2020 to October 2024 were divided into two groups of 51 each using a random number table method.The children in the con-trol group received polyethylene glycol electrolyte powder for intestinal preparation,while those in the observation group received lactulose oral solution combined with polyethylene glycol electrolyte powder for intestinal preparation.The Boston bowel prepara-tion scale(BBPS)was used to evaluate the quality of bowel hygiene in both groups.The time of fiberoptic colonoscopy examination(in and out time,total time),bowel preparation tolerance,colon lesion detection rate,and adverse reaction rate were compared between the two groups.Results The total BBPS score in the observation group was(8.44±0.14)points,which was higher than that in the control((7.78±0.15)points)(t=22.971,P<0.05).Observation group's admission time and exit time,total time were(7.23±0.26)min,(7.10±0.20)min,(16.02±0.23)min,respectively and it was shorter than that in the control((9.01±0.52)min,(8.96±0.36)min,(18.23±0.38)min,respectively)(t=21.865,32.254,35.532,P<0.05).The intestinal preparation tolerance of the observation group was 98.04%(50/51),higher than that of the control(86.27%(44/51))(χ2=4.883,P<0.05).In terms of the detection rate of colon lesions,the observation group was 17.64%(9/51)and the control group was 15.68%(8/51),with comparable data between the two groups(χ2=0.071,P>0.05).The total adverse reaction rate of children in observation group was 1.96%(1/51),which was similar to that in the control(3.92%(2/51)),showing no significant difference(χ2=0.000,P>0.05).Conclusion Fiber colonoscopy is often used in children with abdominal pain,which can better diagnose the disease.Intestinal preparation with lactutose oral solution combined with polyethylene glycol electrolyte powder can improve intestinal cleanliness,promote the smooth progress of examination and reduce adverse reactions.Meanwhile,it is safe and reliable.
Keywords：Abdominal pain in childrenFibercolonoscopyPolyethylene glycol electrolyte powderLactulose oral liquidIn-testinal cleaning qualityTime of fibercolonoscopyIntestinal readiness tolerance
Publication Date：2025-04-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 297-300 )