Efficacy of compound huangbai liquid coating combined with metronidazole in treatment of bacterial vaginitis
Lu Yun
Shan Yuan-yuan
Feng Xiao-xiao
Hao Xue-ping
Abstract：Objective To evaluate the efficacy of compound huangbai liquid coating combined with metronidazole in the treatment of bacterial vaginitis.Methods A total of 96 patients with bacterial vaginitis admitted to Hebi Coal Industry(Group)Co.,Ltd.General Hospital from January 2022 to December 2022 were selected and divided into the control group and the observa-tion group by random number table method,with 48 in each group.Both groups were treated with basic dietary control and lifestyle interventions.The control group was given metronidazole and the observation group was administered compound huangbai liquid coating in addition to metronidazole,and both groups were treated for 7 days.The clinical efficacy,vaginal pH,vaginal cleanliness,flora density and Nugent score in the two groups before and after treatment were observed,and the recurrence rate and adverse re-actions were recorded.Results The total effective rate in the observation group was 95.83%(46/48),which was higher than that of 79.17%(38/48)in the control group,(χ2=6.095,P<0.05).After treatment,the vaginal pH,vaginal cleanliness and flora density of the observation group((1.11±0.02)points,(0.85±0.01)points,(1.10±0.07)points)were lower than those of the control group((1.29±0.17)points,(1.22±0.60)points,(1.22±0.13)points),and the differences were statistically significant(t=7.285,4.272,5.631,P<0.05).After treatment,Nugent scores decreased in both groups and the score of the observation group(2.39±0.61 points)was lower than that of the control group(3.06±1.03 points)(t=3.878,P<0.01).The recurrence rate in the observation group was 10.42%(5/48),which was lower than that of 27.08%(13/48)in the control group(χ2=4.376,P<0.05).No adverse reactions occurred during treat-ment in either group.Conclusion Compound huangbai liquid coating combined with metronidazole has certain clinical effects in the treatment of bacterial vaginitis,and has a low recurrence rate and high safety profile.
Keywords：Bacterial vaginitisCompound huangbai liquid coatingMetronidazole
Publication Date：2025-02-24
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 116-119 )