Effect of individualized nutrition program guided by indirect energy measurement on energy metabolism in patients with shock pneumonia
Liu Lu
Wang Xiao-juan
Miao Lei
Yan Yao
Abstract：Objective To investigate the effect of indirect energy measurement on energy metabolism in patients with shock pneumonia under the guidance of individualized nutrition program.Methods Ninety-six patients with shock pneumonia treated in The Second People's Hospital of Lianyungang from January 2020 to January 2023 were selected as the subjects.The daily resting energy expenditure(REE)values were calculated using indirect calorimetry(energy metabolism monitor).According to the random number table method,these patients were divided into the observation group(n=48)and control group(n=48).The observation group was formulated with an individualized nutritional regimen,while the control group was provided with a homogenized diet regimen.The protein metabolism nutritional indicators,upper arm muscle circumference,body mass index,blood glucose levels and prognostic outcomes were compared between the two groups before and after nutritional support treatment.Results After 2 weeks of treatment,the observation group showed higher levels of total protein(TP),albumin(ALB),prealbumin(PA),upper arm muscle circumference and body mass index(66.42±12.37)g·L-1,(38.44±3.25)g·L-1,(28.37±2.89)g·L-1,(25.96±2.03)cm and(22.93±1.62)kg·m-2 than those of the control group((58.57±11.48)g·L-1,(34.37±3.89)g·L-1,(24.88±3.16)g·L-1,(23.87±1.89)cm and(21.64±1.58)kg·m-2)(t=3.223,5.563,5.646,5.221,3.950,all P<0.05).Meanwhile,the fasting plasma glucose(FPG)and 2-h postprandial blood glucose(2hPG)levels were(6.36±1.02)mmol·L-1,(8.05±1.64)mmol·L-1,respectivley,in the observation group,which were lower than those of the control group((7.54±1.09)mmol·L-1,(9.87±1.52)mmol·L-1)(t=5.476,5.639,both P<0.05).The observation group also had shorter duration of mechanical ventilation((9.09±1.48)d vs(10.37±1.56)d),fewer ICU hospitalization time((15.36±1.78)d vs(17.49±1.67)d),a lower 28-day mortality rate(18.75%vs 27.08%)and a lower incidence of fever(8.33%vs 22.92%)as compared with the control group(t=4.124,6.046,χ2=0.944,3.872,all P<0.05).Conclusion The individualized nutritional regimen guided by indirect calorimetry can effectively improve the nutritional status and prognosis of patients with shock pneumonia.
Keywords：Shock pneumoniaIndirect calorimetric measurementIndividualized nutritional supportEnergy metabolismNutritional status
Publication Date：2024-06-25
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 239-243 )