Effect of the management of specific pathway on antibiotic prophylaxis for class Ⅰ incision in cardiac surgery
SHI Xiu-jin
QIN Ying
FANG Zhen-wei
ZHENG Qing-min
LIU Zhi-jun
WANG Hai-yan
WEI Juan-juan
XU Xiao-yu
LIN Yang
Abstract：Objective: To explore the effect of the management of specific pathway on the utilization of antibacterials and the incidence of postoperative infection in class Ⅰ incision cardiac surgery in our hospital. Methods: The defined daily dose (DDDs) of antibiotics, antimicrobial use density (AUD), consumption fee, types of antibiotics and incidence of postoperative infection before and after management were analyzed retrospectively. Results: After management, AUD decreased by 33.60% (28.77/85.62) year-on-year and 29.06% (23.29/80.14) month-on-month. The consumption fee decreased by 66.02% (185.72/281.30) year-on-year and 52.49% (105.64/201.22) month-on-month. The frequency of medication decreased by 40.49% (4325/10 680) year-on-year and 34.62% (3366/9721) month-on-month. There was no significant difference in incidence of postoperative infection (P > 0.05). At the same time, ideas of cardiac surgeons were changed. Time of antibiotic prophylaxis for some patients with low risk of infection was no more than 24 hours. Conclusion: The management of specific pathway could promote the reasonable antibiotic prophylaxis for class Ⅰincision cardiac surgery and decrease the overuse of antibiotics without high incidence of postoperative infection.
Keywords：Cardiac surgeryAntibiotic prophylaxisPath special managementPostoperative infection
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 298-302 )