Analysis of clinical administration behavior of vancomycin under clinical pharmacy intervention
CHEN Yue
ZHU Man
WANG Xiu-ying
LIU Lei
LUO Ming-yu
CHAI Dong
Abstract：Objective: To investigate the effect of intervention by clinical pharmacists in vancomycin application. Methods:Data of vancomycin therapeutic drug monitoring (TDM) was collected from September 2016 to August 2017 in our neurosurgery department. Compliance rate, timeliness, medication rationality, treatment effect, and result of vancomycin TDM before and after clinical pharmacist's intervention were analyzed. Results: The quantity (before intervention 43 cases, after intervention 92 cases) and timeliness (before intervention 4.87 ± 3.78 d, after intervention 3.23 ± 2.51 d) of vancomycin TDM were improved after the intervention of clinical pharmacists. The course of therapy was shortened by pharmaceutical intervention (before intervention 10.98 ± 10.18 d, after intervention 10.92 ± 7.15 d) while the compliance rate of vancomycin concentration was not risen after intervention. The compliance rate of vancomycin concentration was more correlated with the regimen. Conclusion: The intervention of clinical pharmacists could promote the rational use of medication and improve the treatment efficacy.
Keywords：VancomycinTherapeutic drug monitoringClinical pharmacyNeurosurgery
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 295-297,318 )