Analysis of 210 cases reports of adverse drug reaction of antibacterials
YANG Qiong
LI Li
Abstract：Objective: To investigate the characteristics and patterns of adverse drug reactions (ADR) of antibacterials in our hospital, and provide data references for clinical safety and reasonable use of antibacterials. Methods: A total of 210 cases of ADRs caused by antibacterials, which were reported to the national ADR surveillance, from January 2015 to December 2017 in our hospital were collected for retrospective analysis based on patients' age, sex, route of administration, categories of antibacterials, system/organ involvement, clinical manifestations and ADR distribution. Results: ADR mainly occurred in patients aged 30 – 59 years old, which had the highest rate as 62.86%. About 98.10% of ADR was occurred with the administration route of intravenous infusion. Most ADR (27.62%) was caused by penicillin drugs. Skin and its appendants were the most common, accounting for 54.40%. Severe ADRs mainly consist of rash. New ADRs were mainly caused by cephalosporins. Conclusion: Medical institution should enhance the ADR monitoring and standardize the use of antibacterials in order to promote drug safety and rational use of antibacterials.
Keywords：Antibacterial drugsAdverse drug reactionAnalysisRational drug use
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 291-294 )