One case of Guillain-Barre syndrome caused by monosialotetrahexosylganglioside sodium for injection
YIN Hang
YU Qian
SHAO Dan
Abstract：A 50-year-old male patient with a healthy history was admitted to hospital for brain trauma and was diagnosed as chronic subdural hematoma. The patient was treated with hemostasis, acid suppression, anti-inflammation, nourishing nerves, enhancing immune after admission. Eight days later, chest tightness, dyspnea, chills and fever occurred when intravenous infusion of monosialotetrahexosylganglioside sodium (100 mg, ivgtt, qd) was given. On 10thday, limbs weakness appeared gradually. On 11thday, limbs weakness aggravated, accompanying with dyspnea. Clinical diagnosis was Guillain-Barre syndrome. Monosialotetrahexosylganglioside sodium was considered as suspected drug and stopped. The human immunoglobulin (35 g × 4 d, ivgtt, qd) and methylprednisolone sodium succinate (100 mg × 14 d, 60 mg × 2 d, 40 mg × 2 d, ivgtt, qd) were given to the patient, with assisting rehabilitation training. So far, severe limb movement dysfunction had been inherited, and ventilator assisted breathing was used every now and then.
Keywords：Adverse drug reactionMonosialotetrahexosylganglioside sodium for injectionGuillain-Barre syndrome
Publication Date：2018-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 64-66 )