Analysis of 66 cases of adverse drug reactions induced by intravenous drip of moxifloxacin
JI Zi-chao
ZHAO Huan-yu
Abstract：Objective: To investigate the characteristics and rules of intravenous drip of moxifloxacin in our hospital, and to provide references for the rational use of moxifloxacin in clinic. Methods: Using methods of retrospective investigation and analysis, 66 moxifloxacin intravenous infusion ADR cases during January 2014 – December 2016 in our hospital were descriptive statistical analyzed according to the age and sex of patients, drugs usage, organs and systems involved in ADRs, clinical performance data. Results: In 66 cases of ADR, there were 35 male patients (53.03%) and 31 female patients (46.97%) with mean age of (67.33 ± 20.12). Adverse reactions involved in the nervous system were the most, accounting for 31.87%, followed by skin and its appendages (26.09%), hepatobiliary system (14.49%), etc. The earliest ADR occurred within 10 minutes after administration, while the latest occurred 2 weeks later after administration. Two serious adverse reactions were reported, including drug-induced liver injury (one case), delirium, dysphoria, and convulsion of the limbs (one case). Conclusion: Intravenous infusion of moxifloxacin induced a variety of adverse reactions, although most of them were mild, reversible, it is still necessary to be ware of serious adverse reactions to ensure safe medication, medical personnel should pay enough attentions to drug monitoring.
Keywords：MoxifloxacinIntravenous dripAdverse drug reactionAnalysis
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 353-356 )