Improvement on the operating mode of therapeutic drug monitoring by combined with pharmaceutical care from a renal failure case of multiple antibiotics overdose poisoning
YUN Yun-lei
HUANG Li-feng
MIAO Hai-jun
CHEN Wan-sheng
Abstract：Objective: To explore how to combine therapeutic drug monitoring with pharmaceutical care for improving clinical value, by elaborating the medical process of one case of mental poisoning symptom caused by multiple antibiotics overdose in a transplant kidney failure patient. Methods: We analyzed the reason of adverse events, the omission of medical process and the absence of pharmaceutical care, and then introspected the deficiency of original working pattern and improved it in time. According to new pattern, clinical pharmacists timely monitored the clinical application of some key drugs, and actively communicated the results of blood concentration monitoring with doctors. If the results were out of the therapeutic range, pharmacists should learn the medical history, make a consultation, and then provide advice to the attending physician. The pharmaceutical care would not finish until the outcome of critically ill patients went well. Results: Under hemodialysis, the serum creatinine of the patient became basically stable. The pulmonary infection had been healed, and the psychiatric symptoms alleviated. Conclusion: A good work of clinical pharmacy can be carried actively and timely by combining TDM and pharmaceutical care, the pharmacists should take advantage of professional superiority and provide differentiated services in order to ensure the safety of drug use.
Keywords：VancomycinDrug poisoningPsychiatric symptomTherapeutic drug monitoringPharmaceutical care
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 247-250 )