Clinical analysis of 111 cases of ADR/ADE induced by fluoroquinolones
YIN Hang
XIE Cheng
Abstract：Objective: To retrospectively analyze 111 cases of ADR/ADE caused by fluoroquinolones in our hospital, and to explore its characteristics and regularity. Methods: From January 1, 2014 to June 30, 2016, 111 ADR/ADE reports reported to the National Center for ADR Monitoring by our hospital were analyzed statistically according to the items of the basic situation of patients, the original disease, allergies, drug varieties, the speed of infusion, route of administration, adverse reaction occurred of the time, ADR/ADE involving the system/organ and clinical manifestations, serious adverse reaction results, etc. Results: Among the 111 cases of ADR/ADE induced by fluoroquinolone, there were more female than male, most of them were more than 60 years old; 31 patients had allergy histories; the main drug administration route was intravenous drip; 99.10% of ADR/ADE occured within 60 minutes; the most common system/organ involved were skin and its attachments injures; 14 cases were severe ADR/ADE; none of the speed of infusion was marked. Conclusion: Fluoroquinolones should be strictly used in accordance with drug instructions. Medication care should be strengthened to reduce the serious injury caused by drugs.
Keywords：FluoroquinolonesADR/ADERational drug use
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 163-165,182 )