One case of hyperglycemia caused by torasemide
LI Jiu-xu
CHAI Dong
Abstract：One 73-year-old female patient with type 2 diabetes mellitus and rheumatic heart disease was administrated torasemide (20 mg, tid) for half a month. Her fasting glucose rose up to 18 mmol·L-1, and torasemide was stopped, then the fasting blood glucose and postprandial blood glucose reduced to be about 10 mmol·L-1 and 15 mmol·L-1 respectively. After admission, the patient was given digoxin, warfarin, bisoprolol, sitagliptin, acarbose and subcutaneous injection of insulin detemir before sleep, after treatment for seven days, the fasting glucose and postprandial glucose was controlled at the range from 7.2 to 7.7 mmol·L-1 and from 10.3 to 11.3 mmol·L-1 respectively. The risk factors about diuretics-induced hyperglycemia are dosage, age, duration, and the original blood sugar levels. So clinical pharmacist suggest that type 2 diabetes patients, especially old patients, in the use of thiadiazide diuretics or loop diuretics, should start with the lowest dosage and monitor the potassium and blood sugar closely.
Keywords：TorasemideHyperglycemiaAdverse drug reaction
Publication Date：2017-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 124-125 )