Practice of clinical pharmacist participating in the treatment for a patient with carbapenem-resistant Klebsiella pneumoniae bloodstream infection and acute renal failure
JIANG Jie
SHI Xia-ying
ZHANG Yi-fang
WANG Ling
SHEN Nan-nan
Abstract：One 80-year-old male patient was hospitalized for repeated urinary hesitancy for more than 3 years. After hospitalization, the patient was transferred to the intensive care unit (ICU) because of fever, septic shock and acute renal failure. The imipenem and cilastatin was given to him after entry. And then, the result of blood culture showed carbapenem-resistantKlebsiella pneumoniae (CRKP). Bedside continuous renal replacement therapy (CRRT), anti-infective therapeutic regime was adjusted to meropenem, tigecycline and amikacin due to the deterioration of infection, the decreasing of the urine volume and the increasing of serum creatinine. Clinical pharmacist optimized the therapeutic regimen in respect of designing anti-infection regime, adjusting dose of antibacterial in CRRT, and performed entire pharmaceutical care to the patient. The patient improved markedly and transferred out of ICU without adverse drug events.
Keywords：Carbapenem-resistantKlebsiella pneumoniaeAnti-infective therapyContinuous renal replacement therapyClinical pharmacist
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 377-380 )