Analysis of 107 reports of serious adverse drug reaction/event
ZHOU Peng
JIANG Xiao-qin
CUI Lan
Abstract：Objective:To investigate the report situation and characteristics of serious adverse drug reactions/events (ADRs/ADEs) of a hospital, and to provide reference for improving the quality of reports.Methods: ADRs/ADEs collected by a hospital from 2009 to 2015 were analyzed statistically and retrospectively.Results: In a total of 107 serious ADRs/ADEs, 36 cases (33.64%) were forwarded to the national adverse reaction monitoring center, while 71 cases (66.36%) were not. The elderly patients (41 cases, 38.32%) had the highest incidence of serious ADRs/ADEs. Oral route (67 cases, 57.76%) was the main route of administrations. Most of serious ADRs/ADEs (50 cases, 36.23%) were induced by antimicrobial drugs. About 87 cases (70.73%) involved skin and appendage damage.Conclusion: Attention should be paid to strengthen training of medical staff to improve the quality of reporting and decrease the rate of false positives and false negatives, in order to promote safe, effective and rational use of drugs.
Keywords：Adverse drug reactionAnalysisRational drug use
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 356-358,359 )