Research on the development of the new automatic surveillance module and furosemide-associated pancreatin abnormality
ZHAO Liang
TANG Zhi-hui
GUO Dai-hong
ZHU Man
MA Liang
ZHAO Su-yu
ZHAO Peng-zhi
Abstract：[AbstrAct]Objective:To expand the module of medical organization ADE active surveillance and intelligence assessment alarming system, and explore the feasibility and key factors of utilizing the new module to actively monitor the furosemide-associated pancreatin abnormality.Methods:Adopting analytical method, inpatients taking the target drugs from January to June in 2016 were monitored and the positive predictive value of the system and the occurrence regulations were analyzed, supplemented by artiifcial screening to verify the setting rationality of the exclusive indexes.results: 2356 cases were screened from 6832 cases, and 179 were alarming cases, among which 45 were the positive cases, with the positive alarming rate of 25.14% and the occurrence rate of 1.91%. Nine were the suspected acute pancreatitis cases, with the occurrence rate of 0.38%. The occurrence rates before and after enrolling the evaluable excluded cases showed no obvious difference. ADR mostly occurred within 3 days after medication, and both high dose and low dose could result in the occurrence of ADR.conclusion: The new module can effectively and accurately measure the characteristics and risk factors of the furosemide-associated pancreatin abnormality through reasonably setting the event conifgurator parameters, which can provide foundation for clinical diagnosis and has excellent application prospect.
Keywords：Automatic surveillanceNew moduleFurosemidePancreatin abnormality
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 312-314 )