Analysis of 432 cases of adverse drug reactions

ZHANG Xiao-ying; YE Yin-mei

Abstract：[AbstrAct]Objective:To investigate the characteristics and patterns of the adverse drug reactions (ADRs) in our hospital, and provide references for rational drug use.Methods:A total of 432 ADR reports in our hospital from 2014 to 2015 were collected retrospectively. The data in respect of age and gender of patients, categories of drugs, route of administration, systems and organs involved in ADR were analyzed statistically.results:The ADR occurred mostly in elderly patients and children. Among the 432 cases, 136 kinds of drugs were involved, 171 cases were induced by 32 anti-infective drugs; the ADR was mostly induced by intravenously administered drugs (289 cases) and manifested mainly as lesions of skin and its appendants, damage of digestive system and nervous system.conclusion: On the basis of the concept of patient-centered services and attention of leadership, the work of ADR monitoring was advancing all the time by taking several measures, for promoting patient's medication safety and effectiveness.