Case analysis of the therapy of acute cerebral infarction combined with pulmonary infection
HE Chun-hui
LI Xia
ZHAO Yi-qing
GAO Qiu-fang
GE Chong-yu
Abstract：A 74-year-old man was hospitalized because of acute cerebral infarction, hypertension and pulmonary infection. The patient was administrated with antiplatelet drugs, anti-infective drugs, lipid-regulating drugs and neurotrophic therapy. After admission, the body temperature of the patient increased to 39.2℃. Piperacillin/tazobactam (2.5 g, bid, ivgtt) and cefepime (2.0 g, bid, ivgtt) were prescribed respectively against infection. Due to the poor effect of anti-infection, the patient was administrated with vancomycin (1.0 g, q 12 h, ivgtt). Four days later, the patient's body temperature returned to normal while cough and increased sputum production continued. Cefoperazone/sulbactam(3.0 g, q 8 h, ivgtt) was combined use for anti-infection treatment suggested by clinical pharmacist. And then the situation of patient improved gradually. During the treatment, the patient's aminopherase (ALT and AST) continued to rise. The abnormal liver function was considered to be induced by rosuvastatin. So rosuvastatin was stopped and reduced glutathione (2.4 g, qd, ivgtt) was given to the patient. Five days later, the aminopherase decreased and then returned to the normal level. Finally, the patient was in a stable condition and discharged.
Keywords：Pulmonary infectionAbnormal liver functionCase analysisClinical pharmacist
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 186-187,188 )