The supporting role of astragalus polysaccharide injection in chemotherapy for diffuse large B-cell lymphoma
SHI Yue-jian
ZHOU Wen-jin
ZHENG Cui-ping
CAI Xiao-ping
Abstract：Objective: To observe the supporting effects of astragalus polysaccharide injection in chemotherapy for diffuse large B-cell lymphoma (DLBCL).Methods: Case-control study method was adopted. A total of 76 DLBCL patients were randomly divided into the treatment group (chemotherapy combined with astragalus polysaccharide, 40 patients) and the control group (chemotherapy, 36 patients). After four cycles of chemotherapy, adverse reactions, immunologic function and quality of life situation of two groups were assessed.Results:The number of cases of occurring adverse reactions in respect of leucopenia, decreased hemoglobin, thrombocytopenia, hepatic dysfunction, neurotoxicity, cardiac dysfunction, fatigue in treatment group were signiifcantly less than those in the control group (P < 0.05). After treatment, NK cells and CD4+/CD8+ were signiifcantly increased (P < 0.05), and the quality of life in the treatment group was better than that in control group (P < 0.05).Conclusion: Astragalus polysaccharide combined with chemotherapy can reduce adverse reactions, enhance immunologic function and improve the quality of life in DLBCL patients.
Keywords：Astragalus polysaccharideDiffuse large B-cell lymphomaChemotherapyAdverse reaction
Publication Date：2016-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 137-139,143 )