Analysis of 935 ADR reports in our hospital from 2010 to 2014

XU Wei-jia; GAO Yong; LIANG Shao-long; WU Xue

Abstract：Objective: To analyze and sum up the experience of adverse drug reaction (ADR) monitoring in our hospital, and promote the patient's medication safety and effectiveness.Methods:A total of 935 ADR reports in our hospital from 2010 to 2014 were collected retrospectively. The data in respect of age and gender of patients, categories of drugs, route of administration, systems and organs involved in ADR, clinical manifestations and prognosis were analyzed statistically.Results: The quantity and quality of ADR reports in our hospital improved gradually. Among 935 ADR reports, there were 110 cases (11.76%) of new and severe ADR, and 36 cases (3.85%) were severe ADR; 436 cases (46.63%) were male and 499 cases (53.37%) were female; patients aged from 21 to 50 years accounted for the largest proportion (49.63%); skin and appendages damage was the most frequent ADR (43.84%); the most frequency in suspected drugs was anti-infective drugs (40.64%); the main administration route causing ADR was intravenous administration (78.50%).Conclusion:On the basis of the concept of "patient-centered services" and attention of leadership, the work of ADR monitoring was advancing all the time by taking several measures, such as encouraging the participation of all the pharmacists, for promoting patient's medication safety and effectiveness.