One case of allergic reaction caused by cyclosporine injection
MO Xu
JIA Bo-jun
ZHU Yu
Abstract：One 31-year-old male patient with allergic history of vitamin K1 was diagnosed with acute myeloid leukemia 4 months ago. He accepted allogeneic peripheral blood hematopoietic stem cell transplantation. Cyclosporine injection was applied to prevent graft-versus-host disease (GVHD). Twenty minutes after the infusion of cyclosporine injection, the patient appeared the face and neck redness, lfustered, asthma, shortness of breath and other symptoms. Cyclosporine injection was stopped immediately and the head of the patient was elevated. After the inhalation of oxygen with 3 L·min-1, the patient felt better. The next day he was given cyclosporine injection again to test whether the patient tolerated cyclosporine. The same symptoms appeared again. So tacrolimus was used to prevent GVHD. No allergic reactions happened until he was discharged from the hospital.
Keywords：Cyclosporine injectionAllergic reactionAdverse drug reaction
Publication Date：2015-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 129-130 )