One case of serious anaphylaxis induced by fluconazole injection
DENG Mu-hong
HUANG Fang-fang
CHEN Zhi-jie
LI Xiu-xiu
Abstract：[ABSTRACT]One 45-year-old male patient diagnosed with lung cancer received chemotherapy and radiotherapy. Throat swab culture and stool culture conifrmed fungal infections and lfuconazole injection (100 mg, ivgtt) was given for antifungal therapy. Two minutes after the end of infusion, the patient complained of shiver, hyperpyrexia, suffocation and severe cough, which was considered as severe allergic reaction. Inhalation of oxygen (4 L·min-1), dexamethasone sodium phosphate injection (5 mg, iv), diphenhydramine hydrochloride injection (1 mL, im), diprophylline injection (0.25 g, ivgtt), methylprednisolone sodium succinate for injection(40 mg, iv) and lysine acetylsalicylate for injection (0.9 g, iv) were given. Then the patient recovered gradually and the above symptoms disappeared 3 h later.
Keywords：Lung cancerFluconazole injectionSevere allergic reactionAdverse drug reaction
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 390-391 )