Comparative analysis of intervention effects by clinical pharmacist on the prophylactic use of antibacterials during perioperative period of myomectomy
TIAN Yun
WU Lin
ZHAO Pei-xi
YANG Jing
CAO Fang
Abstract：Objective:To estimate the intervention effects by clinical pharmacist on the use of antibacterials during perioperative period of myomectomy. Methods:The clinical data were collected from 50 patients with myomectomy from July to December in 2012 (before intervention) and 50 patients from January to June in 2013 (after intervention). The rationality of antibacterials application was evaluated thereafter. Results:After intervention by clinical pharmacists, the perioperative prophylactic application of antibacterials for myomectomy signiifcantly improved in respect of antibacterials selection, medication duration and pharmacoeconomics. Before and after intervention, the percentages of cephalosporins use were 42.0% and 72.0%, respectively. The reasonable rate of medication duration of antibacterials rose from 12.0%to 60.0%, the reasonable rate of pharmacoeconomics rose from 50.0%to 86.0%, with statistical signiifcance (P<0.05). The proportion of the total drug cost accounting for the total cost of hospitalization decreased from 51.0% to 49.3%, and the percentage of total antibacterials expense in the total medicine expense decreased from 30.2%to 28.8%. The mean hospitalization stay per patient decreased 1.26 days. Conclusion:The clinical pharmacists' intervention on the prophylactic application of antibacterials was feasible and effective, which can improve the rational application of antibacterials, decrease hospitalization stay and expense. It will promote safe, effective and economical use of antibacterials.
Keywords：Clinical pharmacistAntibacterialsClean-contaminated surgeryInterventionMyomectomy
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 315-317,318 )