Analysis and clinical treatment of respiratory tract spasms induced by tramadol hydrochloride
ZHANG Wen-jing
WAN Si-hui
WANG Zhuo
XIA Yang
BAI Chong
Abstract：One tracheal adenoid cystic carcinoma patient after surgical operation developed asthma and shortness of breath because of over dose use of tramadol hydrochloride. The clinical pharmacists took pharmaceutical care for this speciifc case. According to literature from domestic and aboard, the patient using high dose of tramadol (>1000 mg·d-1) or the patient using tramadol with liver injury could develop asthma, shortness of breath and respiratory depression symptoms. The pharmacists discussed the pharmacology and pharmacokinetics of tramadol and treatment of adverse drug reaction caused by tramadol with doctors. Symptoms of asthma and shortness of breath eventually relieved after withdrawal of tramadol.
Keywords：TramadolRespiratory tract spasmClinical pharmacistPharmaceutical care
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 297-299 )