QT interval prolongation induced by acetylcysteine
LV Juan-li
ZHONG Hua
LIU Zhen-hua
Abstract：One 68-year-old female patient was administrated with acetylcysteine tablets (0.6 g, tid) due to the pulmonary fibrosis. Three days later, the patient complained of chest pain, palpitation and chest tightness. Electrocardiogram showed that paroxysmal atrial tachycardia and ST-T change;the QT interval prolonged and the value of QTc was 503 ms, while the three factors of myocardial infarction, electrolytes and BNP were within the normal range. Then acetylcysteine tablets were stopped immediately, but other medications continued. The next day the patient's uncomfortable symptoms disappeared, and the value of QTc dropped to 446 ms. The patient was discharged with improved condition on the third day after drug withdrawal.
Keywords：AcetylcysteineQT interval prolongationAdverse drug reaction
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：2( 255-256 )