Analysis on 609 ADR reports of our hospital in 2012

XIE Hua; ZHANG Gui-lin; WANG Rong; LI Wen-bin

Abstract：Objective:To investigate the feature, regularity and related factors of adverse drug reactions (ADRs) occurred in our hospital, in order to provide reference for rational medication in clinic. Methods: A total of 609 ADR case reports were collected from January 1 to December 31 in 2012. The reports were classiifed and analyzed statistically in respect of the age and gender of the patients, dosage form, route of administration, the category of drugs, organs or systems involved in ADRs and severe ADRs, etc. Results:Among the 609 ADR cases, 340 cases (55.83%) were male and 269 cases (44.17%) were female. Among 609 ADR cases, 142 patients (23.32%) were more than 70 years old. The ADR incidence rate of intravenous administration was the highest, accounting for 84.73%. Tranexamic acid sodium chloride occupied the ifrst place in top ten ADR warning drugs. There were 159 cases (25.32%) appeared as skin and its appendants damage, which were the most common manifestations. Conclusion:The occurrence of ADRs relates to a variety of factors. Reporting and monitoring of ADRs as well as pharmaceutical care should be strengthened to promote the rational drug use and reduce the occurrence of ADRs.