Retrospective analysis of adverse drug reactions induced by tigecycline
LI Yu-lin
LIANG Zhi-xin
WANG Bin
ZHU Man
LUO Hai-lun
CHEN Liang-an
SHE Dan-yang
Abstract：Objective: To pay more attention to the adverse drug reactions (ADRs) induced by tigecycline and provide references for rational use of drugs. Methods:By reviewing the literatures, the ADRs induced by tigecyline were analyzed in respect of general data, primary disease of the patients, types of ADRs, occurrence time, therapeutic method, prognosis, etc. Meanwhile, a case of tigecycline-induced hypoglycemia was reported. Results: Ten ADRs cases induced by tigecycline were collected. Eight cases of them were pancreatitis, one case of diarrhea, one case of coagulation disorder. A 78-year-old male patient was diagnosed as severe pneumonia, chronic obstructive pulmonary disease, and pulmonary interstitial ifbrosis developing persistent hypoglycemia after intravenous infusion of tigecycline. During the mechanical ventilation, the result of sputum culture was multi-drugs resistant Acinetobacter Bauman. Conclusion:More attention should be paid to adverse events induced by tigecycline to ensure the safety of drug use in clinic.
Keywords：TigecyclineAdverse drug reactionHypoglycemia
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 111-114 )