Pharmaceutical care on a patient with infection after femoral head replacement
ZHANG Jin-ping
GE Wei-hong
LI Yuan-yuan
Abstract：One 59-year-old male patient was admitted to hospital because of swelling and pain for 10 days after left femoral head replacement. The patient received left femoral head replacement 3 months ago and had been feeling notch pain for 10 days with purulent oozing. The patient underwent debridement and prosthesis extraction indwelling, and took pus for bacteria culture. Levolfoxacin and vancomycin were empirically given for anti-infection. Five days later, the results of pus culture showed Escherichia coli. According to the antibiotic sensitivity test results, the clinical pharmacist advised to give cefoperazone sodium and sulbactam sodium for injection. About 10 days later, Escherichia coli was detected in the catheter tip culture again, while C reactive protein and neutrophil increased signiifcantly. On the 20th day after admission, the bacterial culture of incision secretion still showed Escherichia coli, intermediary towards cefoperazone sodium and sulbactam sodium. The clinical pharmacist recommended imipenem and cilastatin sodium as well as incision debridement. Three days later, the result of routine blood test gradually returned to normal and the infection was under control.
Keywords：Postoperative infectionClinical pharmacistPharmaceutical care
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 95-97 )