Determination of tanshinol in Linaoxin capsule by RP-HPLC
HU Hui
PENG Yan
ZHANG Qian
Abstract：Objective:To establish a RP-HPLC method for the determination of tanshinol in Linaoxin capsule. Methods:The analysis was carried out on an Inertsil C18 column (4.6 mm×250 mm, 5 μm), the mobile phase was consisted of methanol and 1%glacial acetic acid (10∶90), and the lfow rate was 1.0 mL·min-1. The detection wavelength was set at 280 nm, and the column temperature was 30℃. Results:The linear range of tanshinol was 10.58-105.80 μg·mL-1 (r=0.999 7). The average recovery was 99.51%with RSD of 1.60%(n=6). Conclusion:The method is simple, rapid, accurate, repeatable, which is suitable for the quality control of Linaoxin capsule.
Keywords：RP-HPLCLinaoxin capsuleTanshinol
Publication Date：2014-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 15-17 )