Application analysis of antibacterials during the period of special rectification in our hospital in 2012

FAN Li-hong; MIAO Cai-yun; GONG Xiao-ming

doi:10.3969/j.issn.1672-8157.2013.05.017

Abstract：Objective:To investigate the clinical application of antibacterials in our hospital during the different periods of special rectiifcation in 2012, so as to provide reference for follow-up management. Methods:The special rectiifcation period was divided to three stages:early stage (May to July 2012), middle stage (August to October 2012) and last stage (November 2012 to January 2013). Data such as the consumption sum, the frequency of medication (DDDs) of antibacterials and the antibiotics use density (AUD) were analyzed in different stages retrospectively. Results:DDDs decreased by 19.83%and 15.54%, AUD decreased by 17.54%and 14.15%, and the utilization rate of antibacterials decreased by 17.60%and 8.75%in the last stage and middle stage of special rectiifcation compared with that in the early stage, respectively. The mean expense of antibacterials decreased from 903.52 Yuan to 843.65 Yuan (decreasing by 59.87 Yuan). The use of special level antibacterials was improved obviously after classiifed management and special rectiifcation, the utilization rate of special level antibacterial agents decreased by 49.06%and 40.17%, and AUD decreased by 20.08%and 12.95%in the last stage and middle stage compared with that in the early stage, respectively. The utilization rate of prophylactic use of antibacterials in classⅠincision operation decreased from 22.22%in the early stage to 16.67%in middle stage and 14.58%in last stage, which met with the criteria demand of less than 30%. In the period of special rectiifcation, microbiological samples detection rate had no signiifcant change, and the positive detection rate was low. Conclusion:The special rectiifcation can signiifcantly improve the rational use of antibacterials in our hospital, but long-term management mechanism of antibacterial application should be taken to strengthen the rational use of antibacterials.