Retrospective analysis of adverse reactions induced by hepatocyte growth-promoting factors
XING Yuan
SONG Cheng-gong
Abstract：Objective:To analyze the adverse drug reaction (ADR) cases induced by hepatocyte growth-promoting factors so as to provide references for rational use of drugs. Methods:Through searching the literatures, the ADRs case reports induced by hepatocyte growth-promoting factors were analyzed in respect of the basic characteristics of the patients, occurrence time and prognosis of ADRs, clinical manifestations and relevance evaluation. Results:There were 21 cases of hypoglycemic reactions induced by hepatocyte growth-promoting factors, which accounted for 34.4%of the total ADRs. Most reactions occurred within 30 minutes of infusion (30 cases, accounting for 49.2%). Most patients returned to normal after active treatment without sequelae and complication. Conclusion: The hepatocyte growth-promoting factors had the repair and secretory effect on impaired pancreatic islet cells. The hypoglycemic reactions induced by hepatocyte growth-promoting factors in treatment of hepatopathy should be paid attention to.
Keywords：Hepatocyte growth-promoting factorsHypoglycemiaAdverse drug reaction
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 276-277,278 )