Analysis of the prophylactic antibacterial agents used in 465 patients with cesarean section
WANG Qing-li
WANG Yong-ling
JIA Ming-lu
Abstract：Objective:To investigate and analyze the application of prophylactic antibacterial agents during perioperative period in cesarean section and provide reference for rational drug use. Methods:A total of 465 cases of cesarean section collected from June to December 2012 were retrospectively analyzed in respect of the patient's general condition, surgical cases, medication time, dose, species, medication duration of antibacterial agents, DDDs and drug use index (DUI). Results:A total of 464 (99.8%) patients were given prophylactic antibacterial agents, 391 (84.3%) patients with one antibacterial agents and 73 (15.8%) patients with the combination of antibacterial agents. A total of 383 cases (82.5%) were given antibacterial agents after cutting the umbilical cord. There were 314 cases (67.7%), 10 cases (2.2%), 140 cases (30.1%) in medication time≥72 h,≤48 h,≤24 h respectively. The top three drugs in terms of DDDs were cefuroxime sodium, cefotiam and ornidazole. Conclusion:The use of antibacterial agents in perioperative patients with cesarean section was basically rational in medication time, species choice, combination drug use, but the medication duration and DUI should be reduced further.
Keywords：Cesarean sectionPerioperative periodAntibacterial agentsRational drug use
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 222-223,224 )