Pharmaceutical care on one patient with infective endocarditis
BI Huang-lei
WANG Li
Abstract：One 33-year-old male patient was admitted to hospital because of fever more than one month and pain at the right lower limb for one week. He was diagnosed as infective endocarditis a month ago, with the blood culture of methicillin resistant Staphylococcus aureus. The temperature of the patient dropped to normal after the treatment for several days and he was discharged from hospital. Then the patient developed fever and was admitted to another hospital. Results of three sets of blood culture and vegetation cultivation were negative. Based on the previous result of blood culture, referring to the guides, clinical pharmacists suggested the combination treatment of vancomycin, nafcillin and rifampin. The effect was poor. Then the mitral valve replacement surgery and neoplasm resection were conducted on the patient. According to low-grade fever, postoperative renal dysfunction of the patient, the anti-infective drug was adjusted to linezolid. After three days, the patient developed fever and leukopenia suspected due to linezolid. Then medication was switched to vancomycin and cephazolin, the adverse reaction disappeared. The patient recovered well after six weeks' anti-infection treatments and was discharged from hospital with no relapse.
Keywords：Clinical pharmacistPharmaceutical careInfective endocarditis
Publication Date：2013-01-01
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：3( 209-211 )