Correlation between post-admission stress-induced hypertension and clinical outcomes after PCI in patients with unstable angina pectoris
ZHANG Puqiang
LIU Xiaoyu
LIU Xiaoling
WANG Hongmei
MI Hongying
Abstract：Objective To investigate the association among stress-induced hypertension(SIH)developed after admission and the incidence of major adverse cardiovascular events(MACE)following percutaneous coronary intervention(PCI),as well as postoperative complications of PCI during hospitalization,in patients with unstable angina pectoris(UAP).Methods The UAP patients(n=875)without a history of hypertension who underwent PCI were consecutively enrolled at Hebei Yiling Hospital from Jan.2021 to Jan.2024.According to the presence of transient blood pressure>140/90 mmHg on admission,the patients were divided into SIH group(n=291)and non-SIH group(n=584).The primary outcome was MACE,including cardiac death,non-fatal myocardial infarction,repeat revascularization and stroke.The secondary outcomes were postoperative complications of coronary angiography,including acute coronary occlusion,pseudoaneurysm,arrhythmia and adverse reactions to contrast medium.The difference in survival rate was analyzed by using Kaplan-Meier curve,and the association between SIH and MACE incidence was evaluated by using Cox proportional hazards regression model within 1 y after PCI.The relationship between SIH and incidence of in-hospital postoperative complications of PCI was assessed by adopted chi-square test.Results There were no significant differences in baseline characteristics between SIH group and non-SIH group.The results of Kaplan-Meier curve analysis revealed a significant difference in the cumulative incidence of MACE within 12 months between SIH group and non-SIH group(Log-rank P=0.028).After adjusting for confounding factors in Cox regression analysis,SIH was found to be associated with an increased risk of MACE(HR=1.45,95%CI:1.01-2.09,P=0.042).The results of sensitivity analysis and subgroup analysis were consistent.The results of Chi-square test indicated no association between SIH and in-hospital postoperative complications of PCI.Conclusion SIH is an dependent risk factor affecting MACE incidence within 1 y after PCI in UAP patients.
Keywords：stress-induced hypertensionunstable angina pectorismajor adverse cardiovascular eventspercutaneous coronary intervention
Publication Date：2026-02-20
Online Publishing Date：2026-03-19(First online date of this platform, not the publication date of the document)
Pages：5( 157-161 )