Correlation between CVAI and coronary heart disease in patients with type 2 diabetes mellitus:a cross-sectional study in Chinese population
WANG Binlu
ZHANG Yueyang
WAN Qin
YANG Xiaoyu
LI Peidong
Abstract:Objective To discuss the correlation between visceral adiposity index(VAI)and coronary atherosclerotic heart disease(CHD)in patients with type 2 diabetes mellitus(T2DM).Methods A total of 3000 patients with T2DM were enrolled in this study in the Affiliated Hospital of Southwest Medical University from Jan.2019 to Dec.2022.Patients lost to follow-up,non-respondents and those who withdrew midway were excluded,with 2575 cases finally included.Through multivariate regression analysis,the potential associations between obesity-related indicators-especially Chinese visceral adiposity index(CVAI),visceral adiposity index(VAI),waist-to-hip ratio(WHR),body mass index(BMI),subcutaneous fat area(SFA),and visceral fat area(VFA)-and the incidence of coronary atherosclerosis were explored.In addition,to comprehensively clarify the relationships among the above indicators,Spearman correlation analysis was performed to evaluate their associations with CHD occurrence in T2DM patients.Results In a cross-sectional study involving 135 patients with CHD,the prevalence of CHD was significantly correlated with CVAI,T1:2.68%,T2:5.94%,T3:7.11%,P<0.001)and waist-to-height ratio(WtHR,T1:4.20%,T2:5.16%,T3:6.74%,P<0.050).The higher the CVAI,the higher the odds ratio(OR)for CHD(T1:reference;T2:OR=2.418,95%CI:1.266~4.620;T3:OR=3.951,95%CI:1.737-8.987).The sensitivity of CVAI for predicting CHD was 68.1%,the specificity was 52.7%,with a 95%CI of 0.572~0.662.Conclusion Among patients with T2DM,abdominal obesity indicators are significantly correlated with CHD risk,among which CVAI exhibits the optimal predictive efficacy.The higher the CVAI,the greater the CHD risk.Moreover,its diagnostic value outperforms that of other indicators,indicating that CVAI can serve as an important basis.
Keywords:type 2 diabetes mellituscoronary heart diseaseabdominal obesity indicatorsChinese visceral adiposity index
Publication Date:2026-01-20
Online Publishing Date:2026-03-25(First online date of this platform, not the publication date of the document)
Pages:7( 64-70 )
