Application value of heart rehabilitation training combined with atorvastatin to coronary heart disease after percutaneous coronary intervention
QI Ran
QIN Lingling
ZHAO Haibo
Abstract：Objective To discuss the application value of heart rehabilitation training combined with atorvastatin to coronary heart disease(CHD)after percutaneous coronary intervention(PCI).Methods CHD patients(n=286)were selected from Beijing Chaoyang Hospital Affiliated to Capital Medical University from Mar.2022 to Feb.2023,all of whom underwent PCI.According to random digital table,they were divided into control group(n=143)and observation group(n=143).The control group was treated with aspirin and clopidogrel after surgery,while the observation group was additionally treated with heart rehabilitation training combined with atorvastatin,with continuous medication for 3 months.The myocardial blood perfusion,coagulation function,exercise capacity,heart function and microcirculation function were compared between 2 groups before treatment and 3 months after treatment.The incidence of major adverse cardiovascular events(MACE)was compared between 2 groups during the 12-month follow-up.Results After treatment,the platelet aggregation rate,fibrinogen,prothrombin time,and corrected coronary flow frame count in observation group were lower than those in control group;the thrombolysis in myocardial infarction(TIMI)flow grade 3,myocardial tissue perfusion grade 3,and coronary blood flow velocity were higher than those in control group(P<0.05).After treatment,both groups showed increased exercise tolerance,prolonged 6-minute walk test(6MWT)distance,and decreased Borg Rating of Perceived Exertion(BRPE)score,with more significant changes in observation group(P<0.05).After treatment,the left ventricular end-diastolic diameter(LVEDD)and left ventricular end-systolic diameter(LVESD)decreased,and left ventricular ejection fraction(LVEF)increased in both groups,and the changes were more obvious in observation group(P<0.05).Compared with control group,observation group had a lower circulatory resistance index,a higher coronary flow reserve index,and a lower incidence of MACE after treatment(P<0.05).Conclusion The heart rehabilitation training combined with atorvastatin can improve exercise capacity,microcirculation and prognosis in CHD patients after PCI.
Keywords：heart rehabilitation trainingatorvastatincoronary heart diseasepercutaneous coronary interventionexercise capacitymicrocirculation
Publication Date：2025-10-20
Online Publishing Date：2025-12-03(First online date of this platform, not the publication date of the document)
Pages：5( 1243-1247 )