Structure, Function of Cardiac Lymphatic Vessels and Repair After Myocardial Infarction
Abstract：The lymphatic vascular system plays an important role in maintaining tissue homeostasis and regulating immune responses to tissue damage and pathogen invasion. The heart has a widespread network of lymphatic vessels, which play an important role in maintaining normal cardiac function. After myocardial infarction (MI), the cardiac lymphatic vessels are damaged, and impaired lymphatic drainage is involved in the processes of cardiac edema, persistent inflammation, and cardiac fibrosis. Regulating lymphatic vessel formation may serve as a target for treating cardiac repair after MI. Clarifying the origin, structure, and regulatory mechanisms of cardiac lymphatic vessels is of great significance for promoting therapeutic approaches that enhance lymphatic vessel generation and repair. Recently, the promotion of lymphatic vessel regeneration and repair has gradually attracted attention. This article reviews the structure, function of cardiac lymphatic vessels, and the progress in therapies that promote lymphatic vessel regeneration to repair cardiac injury after MI.
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Publication Date：2025-07-20
Online Publishing Date：2025-09-09(First online date of this platform, not the publication date of the document)
Pages：3( 891-893 )