Electrocardiography features of acute total occlusion of coronary artery in patients with dialysis for end-stage renal disease complicated by coronary artery disease
Wu Xinjun
Sheng Zhaoxue
Li Yike
Tai Jingmin
Niu Liqiao
Lan Jiang
Gao Yanxiang
Zheng Jingang
Abstract：Objective To analyze the electrocardiography(ECG)features of acute total occlusion of coronary artery(ATO)in patients with dialysis for end-stage renal disease(ESRD)complicated by coronary artery disease(CAD),aiming at early identification,recovering revascularization and improving prognosis.Methods The medical records collected from patients with dialysis for ESRD complicated by CAD in 6 participating centers through utilizing Coronary Revascularization in Patients with End-stage Renal Disease on Dialysis in China:a Nationwide and Multicenter Cohort Study(CRUISE-R)-China's largest cohort.The dialysis patients with ATO of CAD were selected into dialysis group(n=72)from the following hospitals met the inclusion criteria:China-Japan Friendship Hospital,Beijing Chaoyang Hospital(affiliated to Capital Medical University),Xinjiang Autonomous Region People's Hospital,Ningbo First Hospital,Shaoxing People's Hospital and Chengdu Third People's Hospital.The non-dialysis patients with ATO of CAD were consecutively enrolled and matched into non-dialysis group(n=260)from Cardiology Department of China-Japan Friendship Hospital during the same period.The two groups had comparable gender and age distributions(aged from 18 to 80).Based on ECG features in 2 groups,ECG features were analyzed in dialysis patients with ATO of CAD.Results The most frequent ECG features were precordial unstable T waves and ST-segment depression in dialysis group,while ST-segment elevation was the predominant feature in non-dialysis group.Both groups showed consistent incidences of De Winter ST/T complex waves and T-wave inversion.Conclusion In dialysis patients with ATO of CAD,ECG demonstrates that ST-T changes mainly characterized by ST-segment depression and a high prevalence of precordial unstable T waves.ECG can provide early warning for patients with atypical clinical manifestations.Enhanced attention is needed to reduce delays in reperfusion therapy and incidence and mortality of cardiovascular events.
Keywords：Coronary heart diseaseDialysisAcute total occlusion of coronary arteryElectrocardiography
Publication Date：2025-07-20
Online Publishing Date：2025-09-09(First online date of this platform, not the publication date of the document)
Pages：5( 834-838 )