The correlation between serum magnesium level and prognosis in young and middle-aged patients with AMI after emergency PCI
Li Muyuan
Zhang Rui
Liu Baoshan
Li Wenshan
Wang Jian
Abstract：Objective To study the correlation between serum magnesium level and prognosis in young and middle-aged patients with AMI after emergency PCI,and to provide new ideas for clinical evaluation of the condition and improvement of prognosis in young and middle-aged patients with AMI.Methods According to the set inclusion and exclusion criteria,214 young and middle-aged AMI patients aged 18 to 65 years admitted to the Emergency Department of Weifang People's Hospital from January 1,2021 to December 31,2021 were included in the study.All patients underwent emergency PCI after admission.According to the quartiles of serum magnesium levels within 48～72 hours after the onset of acute myocardial infarction,the patients were divided into four groups,and the general data,past history data,AMI-related data,laboratory test results and prognosis of the patients were recorded.Clinical baseline data and prognosis were compared among the four groups,and odds ratios and their 95％confidence intervals were calculated using univariate and multivariate logistic regression.Results Among AMI patients who underwent emergency PCI,those with low serum magnesium levels had more alcohol consumption history,diabetes history,and more severe disease,such as increased proportion of Killip grade Ⅱ-Ⅳ,lower calcium ions,CK-MB,and higher LDL.Low magnesium was an independent risk factor for increased MACE:the incidence of MACE in Q1 group was 12.510 times that in Q4 group(P＜0.001),and the incidence of MACE in Q2 group was 5.221 times that in Q4 group(P=0.005),while there was no significant statistical difference between Q3 group and Q4 group,but no significant correlation between low magnesium and LVEF abnormalities was found.In addition to low magnesium levels,the number of diseased vessels,IRA,and management were also independent risk factors for the development of MACE.Conclusions In young and middle-aged patients with AMI undergoing emergency PCI,low serum magnesium levels were an independent risk factor for the development of MACE,but were not significantly associated with abnormal LVEF.
Keywords：Young and middle-agedAcute myocardial infarctionSerum magnesiumPercutaneous coronary interventionMajor adverse cardiac events
Publication Date：2025-02-20
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 189-194 )