Investigation of the Association Between Frailty and Oral Health in Hospitalized Elderly Hypertensive Patients and Its Influence on Clinical Outcomes
Yu Hao
Ye Xuerong
Chen Hongying
Zhang Zheng
Liu Yingdi
Wang Xueying
Zhu Zhenxia
Xie Wenli
Hu Taohong
Abstract：Objective This study aims to investigate the association between frailty and oral health status in elderly inpatients with hypertension and its impact on clinical prognosis.Method A total of 160 elderly hypertensive patients treated at the Geriatric Department of Electric Power Teaching Hospital of Capital Medical University from January 2021 to January 2022 were selected.According to the Fried scale,the patients were divided into a hypertension with frailty group (n=72) and a non-frailty group (n=88).General information of the two groups was compared,including sex,age,body mass index (BMI),smoking history,drinking history,pulse pressure,total cholesterol (TC),triglycerides (TG),thyroid-stimulating hormone (TSH),fasting plasma glucose (FPG),polypharmacy,denture use,and Geriatric Oral Health Assessment Index (GOHAI) scores.Indicators with significant differences were further analyzed using intergroup difference analysis and multivariate logistic regression to explore the relationship between frailty and oral health in elderly hypertensive inpatients.All patients underwent a 1-year follow-up,and the rehospitalization rate and all-cause mortality were compared between the two groups.Results Compared to the non-frailty group,patients in the frailty group had significantly higher age,pulse pressure,polypharmacy,and denture use (P＜0.05),while BMI,TC,and GOHAI scores were significantly lower (P＜0.05).Multivariate logistic regression analysis showed that low BMI,high denture usage rate,polypharmacy,and low GOHAI scores were independent risk factors for frailty in elderly hypertensive inpatients (P＜0.05).In addition,the 1-year rehospitalization rate was significantly higher in the frailty group thanin the non-frailty group (P＜0.05).Conclusion The frailty status of hospitalized elderly hypertensive patients is closely associated with low BMI,high denture usage,polypharmacy,poor oral health status,and poor oral health may increase the risk of frailty and rehospitalization.Therefore,identifying and screening oral health issues in elderly hypertensive patients,as well as taking proactive interventions,are of great importance in delaying aging and improving patient prognosis.
Keywords：HypertensionGeriatricFrailtyDental health
Publication Date：2024-12-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1520-1523 )