Effects of malnutrition and overweight on outcomes in STEMI patients
Shi Haowen
Wang Yiwen
Lu Yuan
Li Lei
Abstract：Objective To investigate the effects of malnutrition and overweight on ST-elevation myocardial infarction (STEMI) patients with Major Adverse Cardiovascular Events (MACE).Methods A total of 534 STEMI patients admitted to the CCU of the affiliated hospital of Xuzhou Medical University from December 2019 to December 2020 were selected.Assessed by Body Mass Index (BMI) at admission and Controlling Nutritional Status Score (CONUT) were divided into malnutrition non-overweight (n=155);malnutrition overweight (n=224);nutrition non-overweight (n=49) and nutrition overweight (n=106).The baseline data of the four groups and the occurrence of MACE after discharge were compared.Kaplan-Meier curve was drawn and Log-rank was used to test the differences among the four groups.Multivariate Cox regression was used to screen for adverse prognostic factors in STEMI patients.Results During the follow-up period (median 18 months),62 cases of MACE occurred (16 cardiovascular deaths,11 recurrent myocardial infarction,26 unplanned vessel revasculation,and 19 nonfatal strokes).Comparison among the four groups showed that the prognosis of malnutrition non-overweight was the worst (P＜0.05).Multivariate Cox regression analysis showed that malnutrition non-overweight (HR=2.048,95％CI:1.235～3.396,P=0.005),KILLIP Ⅱ～Ⅳ(HR=2.323,95％CI:1.126～4.793,P=0.023),smoking history(HR=2.681,95％CI:1.484～4.844,P=0.001),and age＞55 years old (HR=3.447,95％CI:1.454～8.173,P=0.005) were independent risk factors for poor prognosis in STEMI patients.Conclusion Malnutrition non-overweight is an independent risk factor for poor prognosis in STEMI patients.
Keywords：MalnutritionOverweightSTEMIMajor adverse cardiovascular events
Publication Date：2024-12-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 1435-1440 )