Analysis of the Burden and Trends of Chronic Obstructive Pulmonary Disease in China,Japan and Ko-rea,1990-2021
Li Yang
Ren Lian
Abstract：Objective Chronic obstructive pulmonary disease(COPD)patients in China account for one-fourth of the total number of COPD patients in the world,which has resulted in a serious economic burden of disease.The purpose of this paper is to compare the disease burden of COPD in China,Japan,South Korea,and globally,and to analyze the incidence,prevalence,death,and disability-adjusted life year(DALY)of COPD in China,Japan,South Korea,and globally,as well as the corresponding temporal trends from 1990 to 2021.Methods Using Global Burden of Disease Study 2021(GBD 2021)data,Joinpoint(5.2.0)software was used to calculate the annual percent change(APC)and average annual percent change(AAPC).Average annual percent change(APC)and Average annual percent change(AAPC)were calculated using Joinpoint(5.2.0)software to analyze and compare the long-term trends of COPD disease burden and the impact of risk factors on COPD-related mortality and DALY in China,Japan,Korea,and globally.Results Compared with 1990,the number of COPD incidence and prevalence increased in 2021 in China,Japan,Korea,and globally;deaths due to COPD increased,and DALY increased in Japan,Korea,and globally,but DALY in China decreased from 2609.767(2279.056,2921.635)million person-years in 1990 to 2364.032(1999.866,2792.193)million person-years.The prevalence of COPD in China in 2021 is close to that of the world and higher than that of Japan and South Korea;China's mortality,and DALY rates are higher than those of Japan and South Korea.Age-standardized rates of COPD(incidence,prevalence,mortality,DALY)continued to decline in China,Japan,and globally from 1990 to 2021;China had the largest average annual decline[incidence AAPC:-0.7361(-0.7446,-0.7278),prevalence AAPC:-0.3256(-0.3353,-0.3170),mortality AAPC:-3.6895(-3.7513,-3.6175),and DALY APCC:-3.6351(-3.6821,-3.5865)];Korea's mortality rate and DALY were also on a downward trend,but incidence[AAPC:0.0609(0.0426,0.0795)]and prevalence[AAPC:0.2246(0.2020,0.2455)]were increased.The primary risk factor for COPD mortality and DALY was smoking,and ambient particulate matter pollution was the main risk factor for COPD mortality and DALY in Chinese women.Conclusion Compared with Japan and South Korea,the incidence,prevalence,mortality,and DALY of COPD in China from 1990 to 2021 were still high,but with the largest average annual decrease.COPD is still an important public health problem in China,and cigarette smoking is an important factor contributing to death and DALY in COPD patients.In the future,tobacco control should continue to be actively promoted,environmental management should be strengthened,and lung function tests should be carried out in high-risk groups such as smoking men for early diagnosis and treatment.
Keywords：Chronic obstructive pulmonary disease(COPD)Disease burdenDisability adjusted life year(DALY)Trends
Publication Date：2024-11-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：6( 1289-1294 )