Visual analysis of research characteristics and hotspots evolution of therapeutic angiogenesis in ischemic heart disease
Gong Xiao
Zheng Liying
Han Senfu
Wang Rumeng
Xue Mei
Abstract：Objective To explore the research hotspots and frontiers of therapeutic revascularization in the field of ischemic heart disease based on bibliometric analysis.Methods Related articles were retrieved from the Web of Science Core Collection.CiteSpace software visually analyzed authors,countries,research institutions,keywords,etc.Results A total of 2942 publications were identified.The number of publications on this topic is increasing annually.The United States and China were the most prolific countries in this field.Harvard University,the University of California,and Nanjing Medical University were the most prolific institutions.Circulation and Circulation Research were the journals with the most citations.Research has focused on growth factors,gene therapy,and progenitor cell/stem cell transplantation for the treatment of myocardial infarction and other related diseases.Moreover,innovative alternative therapies(miRNA,extracellular vesicles,and bioengineered materials),molecular mechanisms(inflammation and oxidative stress),and molecular imaging may be the focus of future research.Multidisciplinary integration is a developmental trend in this field.Conclusion The research of therapeutic neovascularization in the field of ischemic heart disease is developing continuously,and its theoretical system has been preliminarily constructed,and a number of valuable research themes and high-potential hotspots have been refined,which have good research prospects.
Keywords：Ischemic heart diseaseTherapeutic AngiogenesisBibliometric analysisVisual analysis
Publication Date：2024-11-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1281-1284 )