Related factors and predictive value of no-reflow/slow flow in patients with acute myocardial infarction after percutaneous coronary intervention
Zhao Wei
Yang Xiaolong
Jin Long
Ma Hong'en
Abstract：Objective To analyze the related factors and predictive efficacy of no-reflow/slow flow in patients with acute myocardial infarction(AMI)after percutaneous coronary intervention(PCI),and provide reference for early clinical intervention.Methods AMI patients undergone PCI(n=115)were retrospectively analyzed in the Ninth Hospital of Xi'an City from Mar.2021 to Mar.2023.The patients were divided,according to whether no-reflow/slow flow occurrence after PCI or not,into no-reflow/slow flow group and normal group.The clinical materials and results of laboratory examination were compared between 2 groups.The factors related to no-reflow/slow flow were analyzed by using multi-factor Logistic regression analysis in AMI patients after PCI.The predictive value of related factors to no-reflow/slow flow was analyzed by using ROC curve.Results The results of single-factor Logistic regression analysis showed that age,blood sugar,systolic blood pressure(SBP),disease onset time to PCI,heart rate(HR),modified shock index(MSI),D-dimer(D-D)and monocyte/high-density lipoprotein-cholesterol ratio(MHR)were correlated to no-reflow/slow flow in AMI patients after PCI(P＜0.05).The results of multi-factor Logistic regression analysis showed that blood sugar(OR=2.888,95％CI:1.274～6.547),disease onset time to PCI(OR=3.881,95％CI:1.625～9.270),MSI(OR=54.341,95％CI:10.178～290.127),D-D(OR=35.801,95％CI:7.021～182.558)and MHR(OR=2.048,95％CI:1.502～2.795)were independent risk factors for no-reflow/slow flow in AMI patients after PCI(P＜0.05).The results of ROC curve analysis showed that above risk factors had some predictive value to no-reflow/slow flow in AMI patients after PCI.Conclusion Blood sugar,disease onset time to PCI,MSI,D-D and MHR are correlated to no-reflow/slow flow in AMI patients after PCI,and have some predictive value.
Keywords：Acute myocardial infarctionPercutaneous coronary interventionNo-reflow/slow flow
Publication Date：2024-09-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：4( 1124-1127 )