Incomplete revascularizationin patients with diabetes mellitus complicated by multi-vessel disease of acute coronary syndrome in different ages:an analysis on prognosis
Liu Yang
Chen Qi
Ji Jinrui
Xue Bin
Wu Lei
Wan Dongyu
Liu Hengliang
Abstract：Objective To discuss the influence of incomplete revascularization(IR)on prognosis in patients with diabetes mellitus(DM)complicated by multi-vessel disease of acute coronary syndrome(ACS-MVD)in different ages after percutaneous coronary intervention(PCI).Methods The continuous data of IR was retrospectively analyzed in DM patients complicated by ACS-MVD undergone PCI in Zhengzhou People's Hospital from Jan.2011 to Dec.2019.The patients were divided,according to age,into group A(n=306,aged from 38 to 59,52.37±7.44),group B(n=204,aged from 60 to 79,71.89±8.79)and group C(n=137,aged from 82 to 94,86.87±5.77).The incidence ratesof 36-month primary endpoint events including all-cause death,cardiac death and myocardial infarction(MI)and major adverse cardiovascular and cerebrovascular events(MACCE)including cardiac death,MI,revascularization,in-stentthrombosis and stroke were analyzed.Results The incidence of complete revascularization(CR)was significantly lower in group C than that in groups B and A(40.17％vs.52.22％vs.50.96％,P＜0.001).The differences in all-cause death(18.25％vs.10.29％vs.10.46％,P=0.043),cardiac death(16.79％vs.9.31％vs.6.86％,P=0.005)and MI(15.33％vs.8.33％vs.0.65％,P＜0.001)had statisticalsignificance among 3 groups.The differences in MACCE incidence(56.20％vs.41.67％vs.19.28％,P＜0.001),CR rate(18.98％vs.20.10％vs.8.50％,P＜0.001)and recurrence rate of angina pectoris(24.09％vs.30.39％vs.19.61％,P=0.020)were significant among 3 groups.The incidence of stroke and re-hospitalization rate were higher in group C than those in groups B and A(all P＜0.05).Conclusion The coronary artery lesions are complex in very old DM patients complicated by ACS,and MACCE incidence rates are significantly higher in very old patients than those in non-elderly and elderly patientsafter 1R surgery.
Keywords：Acute coronary syndromeDiabetes mellitusMulti-vessel lesionsPercutaneous coronary intervention
Publication Date：2024-09-28
Online Publishing Date：2025-08-15(First online date of this platform, not the publication date of the document)
Pages：5( 1060-1064 )